As I wrote below, don't jump the gun. There are quite a few new generations of CPUs to come up soon.

I recommend to wait a little until Kaby Lake and Summit Ridge are released (January) and easily available (spring 2017). Then the prices will cool down and you could make a real good bargain on Haswell or Skylake systems.

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I would love to see HCF1 protein folding and interaction simulations to help my little boy... someday.

Sounds like a plan, thanks!

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Cruncher/Learner in progress.

Apparently AMD's Summit Ridge (Zen) CPU's are due in Q1 (Jan - Mar 2017). The high end CPU's are rumoured to be called Ryzen with the server processors expected to support 64 PCIe lanes at PCIe3 (per socket).
We might see that scaled down to 32 lanes for mid range processors (only expected to support two GPU's), but if they support 64lanes for high end/enthusiast CPU's Intel will have a fight on their hands in the high end gaming/crunching processor market, if not the mid-range and server market too.
It's already known that AMD will support PCIE3, DDR4 and their CPU's cache will be much faster than previous generations - less chance of GPU bottlenecks.
Anyway, when AMD release their Zen processors and when there are enough around (which might not immediately happen) we should see sufficient competition to force better performance products at lower prices. Worth waiting for.

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Apparently AMD's Summit Ridge (Zen) CPU's are due in Q1 (Jan - Mar 2017). The high end CPU's are rumoured to be called Ryzen with the server processors expected to support 64 PCIe lanes at PCIe3 (per socket).
We might see that scaled down to 32 lanes for mid range processors (only expected to support two GPU's), but if they support 64lanes for high end/enthusiast CPU's Intel will have a fight on their hands in the high end gaming/crunching processor market, if not the mid-range and server market too.
It's already known that AMD will support PCIE3, DDR4 and their CPU's cache will be much faster than previous generations - less chance of GPU bottlenecks.
Anyway, when AMD release their Zen processors and when there are enough around (which might not immediately happen) we should see sufficient competition to force better performance products at lower prices. Worth waiting for.

+1

I definitely think it's worth it to wait for AMD's new offers, if anything intel's prices will lower if you don't want AMD. Personally this time around AMD's offering look very very appealing.

Apparently AMD's Summit Ridge (Zen) CPU's are due in Q1 (Jan - Mar 2017). The high end CPU's are rumoured to be called Ryzen with the server processors expected to support 64 PCIe lanes at PCIe3 (per socket).
We might see that scaled down to 32 lanes for mid range processors (only expected to support two GPU's), but if they support 64lanes for high end/enthusiast CPU's Intel will have a fight on their hands in the high end gaming/crunching processor market, if not the mid-range and server market too.
It's already known that AMD will support PCIE3, DDR4 and their CPU's cache will be much faster than previous generations - less chance of GPU bottlenecks.
Anyway, when AMD release their Zen processors and when there are enough around (which might not immediately happen) we should see sufficient competition to force better performance products at lower prices. Worth waiting for.

Funny you should mention Zen, here's a new (12/13/2016) and interesting video by AMD talking about Ryzen.
On schedule, fast, efficient and it looks like the first Ryzen will be on the desktop (skip to 20:00 on the video):

https://youtu.be/4DEfj2MRLtA

8cores/16threads for 95W that matches (in carefully selected performance areas) a 16thread 140W Intel CPU costing £1100 is noteworthy because performance ways its competitive, in terms of power usage it's very competitive and no doubt the price will be lower.
Didn't see any mention of PCIe lanes. So they are keeping the lid on that.
The 4MB L2 cache is low but the 16MB L3 cache will likely help support GPU compute/reduce multi GPU bottlenecking in that area, and hints that the PCIe lane count will be high rather than low. While PCIe lane support for Ryzen might depend on how good the CPU actually is, AMD need to give us 64 PCIe lanes; they will be competing with 200-series Intel based systems which are likely to increase PCIe lane count as well. At the i3/i5 end of the markets we might even see better PCIe support from both Intel and AMD.

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FAQ's

HOW TO:
- Opt out of Beta Tests
- Ask for Help