https://www.scientificlinux.org/ I'm just thinking that CERN takes part to put together Scientific Linux. CERN also has a BOINC Project http://lhcathome.cern.ch/lhcathome/ LHC@home. I've had troubles with a few Linux Distros, & am currently looking for something that doesn't turn over one failed WU after the next. It could be that there are driver issues, heat issues, boinc-client issues. But I've run GPUGRID with Linux w/o all these failed WU's just recently & I don't have these problems with Windows. I know that GPUGRID.net isn't LHC@home, but if something works well somewhere, maybe it'll work well elsewhere. But I'm not so keen to try, unless it actually is. Does anyone know???

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Personally, I would pick a linux distro depending on its existing user base; Usually this highens the chances that drivers are supported (either out of the box or by 3rd party vendors) and/or that workarounds to any problem can easily found by google-ing. Ability to run GPUGRID depends on NVIDIA libraries, so it will not be related to LHC-specific fixes (if any).